Output Chart and Table for Natural Products or Drugs using OTTER


The Output of OTTER include 2 ECharts HTML, 1 CSV Table, and 1 Data File for R Heatmap:


1. Output Chart and Table for Celastrol using OTTER with the keyword "reactive oxygen species"

RNA-Seq Output : RNA-Seq Output for cells treated with Celastrol

Input Symbol List : Differentially expressed genes from cells treated with Celastrol

Output PPI Chart : Protein-protein interaction Chart for Celastrol ( Top 50 )


Output Heatmap : Heatmap with Scores and Ranking for Celastrol ( Top 50 )

Output PPI Chart : Protein-protein interaction Chart for Celastrol ( Top 20 )

Output Heatmap : Heatmap with Scores and Ranking for Celastrol ( Top 20 )

2. Output Chart and Table for Doxorubicin using OTTER with the keyword "anticancer"

RNA-Seq Output : RNA-Seq Output for cells treated with Doxorubicin

Input Symbol List : Differentially expressed genes from cells treated with Doxorubicin

Output PPI Chart : Protein-protein interaction Chart for Doxorubicin ( Top 50 )


Output Heatmap : Heatmap with Scores and Ranking for Doxorubicin ( Top 50 )

Output PPI Chart : Protein-protein interaction Chart for Doxorubicin ( Top 30 )

Output Heatmap : Heatmap with Scores and Ranking for Doxorubicin ( Top 30 )

3. Output Chart and Table for Tamoxifen using OTTER with the keyword "breast"

RNA-Seq Output : RNA-Seq Output for cells treated with Tamoxifen

Input Symbol List : Differentially expressed genes from cells treated with Tamoxifen

Output PPI Chart : Protein-protein interaction Chart for Tamoxifen ( Top 50 )


Output Heatmap : Heatmap with Scores and Ranking for Tamoxifen ( Top 50 )

Output PPI Chart : Protein-protein interaction Chart for Tamoxifen ( Top 30 )

Output Heatmap : Heatmap with Scores and Ranking for Tamoxifen ( Top 30 )

Due to space limitations, other examples are not listed here.


Academic users can use Output Charts and Tables of OTTER in publication or presentation.

Correspondence : Dr. Hao Zhang, Chemical Biology Research Center

Shanghai Institute of Materia Medica, Chinese Academy of Sciences